| Cruz AF, Fonseca NA, Moura V, Simoes S, Moreira JN. |
Targeting cancer stem cells and non-stem cancer cells: the potential of lipid-based nanoparticles. |
| Current Pharmaceutical Design. 23 (2017) [Epub ahead of print] |
| Fonseca NA, Cruz AF, Moura V, Simões S, Moreira JN. |
The cancer stem cell phenotype as a determinant factor of the heterotypic nature of breast tumors. |
| Critical Reviews in Oncology: Hematology. 113:111-121 (2017). Epub 2017 Mar 16. |
| Gregório AC, Fonseca NA, Moura V, Lacerda M, Figueiredo P, Simões S, Dias S, Moreira JN. |
Inoculated Cell Density as a Determinant Factor of the Growth Dynamics and Metastatic Efficiency of a Breast Cancer Murine Model. |
| PLoS One. 11(11):e0165817 (2016). eCollection 2016. |
| Fonseca NA, Rodrigues AS, Rodrigues-Santos P, Alves V, Gregório AC, Valério-Fernandes Â, Gomes-da-Silva LC, Rosa MS, Moura V, Ramalho-Santos J, Simões S, Moreira JN. |
Nucleolin overexpression in breast cancer cell sub-populations with different stem-like phenotype enables targeted intracellular delivery of synergistic drug combination. |
| Biomaterials. 69:76-88 (2015). Epub 2015 Aug 6. |
| Fonseca NA, Gomes-da-Silva LC, Moura V, Simões S, Moreira JN. |
Simultaneous active intracellular delivery of doxorubicin and C6-ceramide shifts the additive/antagonistic drug interaction of non-encapsulated combination. |
| Journal of Controlled Release. 196:122-131 (2014). Epub 2014 Oct 10. |
| Fonseca NA, Gregório AC, Valério-Fernandes A, Simões S, Moreira JN. |
Bridging cancer biology and the patients’ needs with nanotechnology-based approaches. |
| Cancer Treatment Reviews. 40(5):626-35 (2014). Epub 2014 Feb 22. Review. |
| Gomes-da-Silva LC, Santos AO, Bimbo LM, Moura V, Ramalho JS, Pedroso de Lima MC, Simões S, Moreira JN. |
Toward a siRNA-containing nanoparticle targeted to breast cancer cells and the tumor microenvironment. |
| International Journal of Pharmaceutics. 434(1-2):9-19 (2012). Epub 2012 May 19. |
| Gomes-da-Silva LC, Fonseca NA, Moura V, Pedroso de Lima MC, Simões S, Moreira JN. |
Lipid-based nanoparticles for siRNA delivery in cancer therapy: paradigms and challenges. |
| Accounts of Chemical Research. 45(7):1163-71 (2012). Epub 2012 May 8. |
| Moura V, Lacerda M, Figueiredo P, Corvo ML, Cruz ME, Soares R, de Lima MC, Simões S, Moreira JN. |
Targeted and intracellular triggered delivery of therapeutics to cancer cells and the tumor microenvironment: impact on the treatment of breast cancer. |
| Breast Cancer Research and Treatment. 133(1):61-73 (2012). (IF: 4.859; Ranking in the category of Oncology: 34; quartile Q1) |
| Mendonça LS, Moreira JN, de Lima MC, Simões S. |
Co-encapsulation of anti-BCR-ABL siRNA and imatinib mesylate in transferrin receptor-targeted sterically stabilized liposomes for chronic myeloid leukemia treatment. |
| Biotechnology and Bioengineering. 107(5):884-93 (2010). (IF: 3.700; Ranking in the category of Biotechnology and Applied Microbiology: 34; quartile Q1) |
| Pinto AC, Moreira JN, Simões S. |
Liposomal imatinib-mitoxantrone combination: formulation development and therapeutic evaluation in an animal model of prostate cancer. |
| Prostate. 71(1):81-90 (2011). (IF: 3.377; Ranking in the category of UROLOGY & NEPHROLOGY: 13; quartile Q1) |
| Pinto AC, Ângelo S, Moreira JN, Simões S. |
Schedule treatment design and quantitative in vitro evaluation of chemotherapeutic combinations for metastatic prostate cancer therapy. |
| Cancer Chemotherapy and Pharmacology, 67(2):275-284 (2011). (IF: 2.759; Ranking in the category of ONCOLOGY: 84; quartile Q2) |
| Santos AO, Gomes da Silva LC, Bimbo LM, Pedroso de Lima MC, Simões S, Moreira JN. |
Design of peptide-targeted liposomes containing nucleic acids. |
| Biochimica et Biophysica Acta, 1798(3):433-441 (2010). (IF: 4.647; Ranking in the category of Biochemistry and Molecular Biology: 64; quartile Q1) |
| Mendonça L, Firmino F, Moreira JN, Pedroso de Lima MC, Simões S. |
Transferrin receptor-targeted liposomes encapsulating anti-BCR-ABL siRNA or asODN for Chronic Myeloid Leukemia treatment. |
| Bioconjugate Chemistry, 21(1): 157-168 (2010). (IF: 5.002; Ranking in the category of Biochemistry and Molecular Biology: 56; quartile Q1) |
| Cardoso A, Trabulo S, Moreira JN, Düzgüneş N, Pedroso de Lima MC. |
Targeted lipoplexes for siRNA delivery |
| Methods in Enzymology, 465:267-287 (2009). (IF: 1.626; Ranking in the category of BIOCHEMISTRY & MOLECULAR BIOLOGY: 213; quartile Q3) |
| Pinto AC, Moreira JN, Simões S. |
Ciprofloxacin sensitizes a hormone-refractory prostate cancer cell line to doxorubicin and docetaxel treatment on a schedule-dependent manner. |
| Cancer Chemotherapy and Pharmacology, 64(3):445-454 (2009). (IF: 2.759; Ranking in the category of ONCOLOGY: 84; quartile Q2) |
| Moreira JN, Santos A, Moura V, Pedroso de Lima MC, Simões S. |
Non-viral lipid-based nanoparticles for cancer systemic gene silencing. |
| Journal of Nanoscience and Nanotechnology, 8(5):2187–2204 (2008). (IF: 1.351; Ranking in the category of MATERIALS SCIENCE, MULTIDISCIPLINARY: 94; quartile Q2) |
| Fonseca C, Moreira JN, Ciudad CJ, Pedroso de Lima MC, Simões S. |
Targeting of sterically stabilized pH-sensitive liposomes to human T-leukemia cells |
| European Journal of Pharmaceutics and Biopharmaceutics, 59(2):359-366 (2005). (IF: 4.304; Ranking in the category of PHARMACOLOGY & PHARMACY: 37; quartile Q1) |
| Simões S, Moreira JN, Fonseca C, Nejat Düzgünes N, Pedroso de Lima MC. |
On the formulation of pH-sensitive liposomes with long circulation times. |
| Advanced Drug Delivery Reviews, 56(7):947-965 (2004). (IF: 13.577; Ranking in the category of PHARMACOLOGY & PHARMACY: 4; quartile Q1) |
| Moreira JN, Ishida T, Gaspar R, Allen TM. |
Use of the post-insertion technique to insert peptide ligands into pre-formed stealth liposomes with retention of binding activity and cytotoxicity. |
| Pharmaceutical Research, 19(3):265-269 (2002). (IF: 4.456; Ranking in the category of PHARMACOLOGY & PHARMACY: 33; quartile Q1) |
| Allen TM, Sapra P, Moase E, Moreira J, Iden D. |
Adventures in targeting. |
| Journal of Liposome Research, 12(1-2):5-12 (2002). (IF: 1.823; Ranking in the category of PHARMACOLOGY & PHARMACY: 152; quartile Q3) |
| Moreira JN, Gaspar R, Allen TM. |
Targeting Stealth liposomes in a murine model of human small cell lung cancer. |
| Biochimica et Biophysica Acta, 1515(2):167-176 (2001). (IF: 4.647; Ranking in the category of Biochemistry and Molecular Biology: 64; quartile Q1) |
| Moreira JN, Hansen CB, Gaspar R, Allen TM. |
A growth factor antagonist as a targeting agent for sterically stabilized liposomes in human small cell lung cancer. |
| Biochimica et Biophysica Acta, 1514(2):303-317 (2001). (IF: 4.647; Ranking in the category of Biochemistry and Molecular Biology: 64; quartile Q1) |
| Slepushkin VA, Simões S, Dazin P, Newman MS, Guo LS, Pedroso de Lima MC, Düzgüneş N. |
Sterically stabilized pH-sensitive liposomes. Intracellular delivery of aqueous contents and prolonged circulation in vivo. |
| Journal of Biological Chemistry, 272(4):2382-2388 (1997). (IF: 5.328; Ranking in the category of Biochemistry and Molecular Biology: 50; quartile Q1) |
